ZEKOCID DSR CAPSULE is a combination of Domperidone and Omeprazole which belongs to the group of medicines called Prokinetic Drugs and Proton pump inhibitors respectively. It is used to treat peptic ulcers, gastroesophageal reflux disease (GERD) and Zollinger-Ellison syndrome (tumours in pancreas causing the stomach to secrete more acid).
Peptic ulcers are painful sores that develop on the linings of the stomach, esophagus and/or intestines. It causes severe stomach pain with sensation of flatulence, indigestion, vomiting and fatigue.
ZEKOCID DSR CAPSULE is effective in treating peptic ulcer caused either due to stomach infection (H. pylori infection) or due to prolong use of non-steroidal anti-inflammatory drugs (such as ibuprofen, aceclofenac).
GERD is a chronic digestive disease in which the acid from the stomach frequently flows into the esophagus leading to irritation of lining of food pipe. Symptoms include heartburn, chest pain, nausea, sensation of lump in throat and stomach discomfort.
ZEKOCID DSR CAPSULE acts by reducing the production of gastric acid. It also speeds up the movement of food from the stomach to the intestines, thereby reducing the signs of nausea, vomiting and acid reflux. Due to these actions, it can also reduce the unpleasant signs of GI tract such as nausea, vomiting, indigestion, burping, bloating, acidity or heartburn.
ZEKOCID DSR CAPSULE is suitable for use both in adults and in children (aged 12 years or above weighing 35 kg or more). It should be taken at least 15-30 minutes before meals. During treatment with ZEKOCID DSR CAPSULE your doctor will closely monitor your kidney functions, liver functions and blood magnesium levels to avoid the risk of unwanted side effects.
Before taking ZEKOCID DSR CAPSULE inform your doctor if you have any liver, kidney or heart problems. You must also inform your doctor if you have any blockage or tears in the gut or have weak bones.
ZEKOCID DSR CAPSULE is not recommended for use in patients having bleeding from the gut. Consult your doctor before taking ZEKOCID DSR CAPSULE if you are pregnant or breastfeeding. The most common side effects of taking ZEKOCID DSR CAPSULE are dryness of mouth, constipation and flatulence. Consult your doctor if any of these side effect bothers you.
You must also inform your doctor immediately if you experience any abnormal signs such as unusual tiredness, abnormal muscle movements, dizziness, confusion, disorientation, irregular heartbeat, fragile bones, bloody stools or vomits or sudden weight loss.

USES OF ZEKOCID DSR CAPSULE
It is used in adults and in children (aged 12 years or older weighing 35 kg or more) to treat:
• Peptic ulcers
• Gastrointestinal Reflux disease (GERD)
• Zollinger-Ellison syndrome (tumours in pancreas causing the stomach to secrete more acid)
• Nausea and Vomiting
• Acidity, Heartburn, Indigestion, Burping, Bloating

HOW ZEKOCID DSR CAPSULE WORKS
ZEKOCID DSR CAPSULE contains two medicines namely domperidone and omeprazole. Domperidone is a prokinetic medicine with anti-emetic properties. It works by blocking the actions of a chemical messenger called dopamine in the gut and across the brain and spinal cord.
This action stimulates the gut, reduces acid reflux and speeds up the movements of food from the stomach into the intestines. It also blocks the transmission of nerve signals between the vomiting centres and the brain which reduces the onset of nausea and vomiting.
Omeprazole is a proton pump inhibitor. It reduces gastric acid secretion by the blocking the actions of a protein membrane called H+K+Atpase (proton pump) present in the lining of the stomach.
By reducing stomach acid production, ZEKOCID DSR CAPSULE prevents the worsening of ulcers, heals the existing ulcers and esophageal lesions and provides relief from the unpleasant symptoms of GI tract (such as acidity, bloating, burping and indigestion).

DIRECTIONS FOR USE
Take ZEKOCID DSR CAPSULE 15-30 minutes before meals or as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine.
Your doctor will decide the correct dose and duration of therapy for you depending upon your age, body weight and disease condition. Do not stop taking ZEKOCID DSR CAPSULE unless your doctor advice you to stop.

SIDE EFFECTS OF ZEKOCID DSR CAPSULE
COMMON
• headache
• diarrhea, stomach pain, constipation, flatulence
• nausea, vomiting
• benign polyps in the stomach
• dry mouth

UNCOMMON
• low sex drive
• dizziness, drowsiness
• anxiety, sleeplessness
• skin rash or itchiness
• breast enlargement in both men and in women
• feeling weak
• swelling of body parts (oedema)
• fragile bones (risk of bone fracture)
• abnormal liver function tests